Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dab1  disabled 1   (Synonyms: C630028C02Rik)
Results	Reference
1	J:137048 Assadi AH, Zhang G, McNeil R, Clark GD, D'Arcangelo G, Pafah1b2 mutations suppress the development of hydrocephalus in compound Pafah1b1; Reln and Pafah1b1; Dab1 mutant mice. Neurosci Lett. 2008 Jul 4;439(1):100-5
1	J:258876 Booler HS, Pagalday-Vergara V, Williams JL, Hopkinson M, Brown SC, Evidence of early defects in Cajal-Retzius cell localization during brain development in a mouse model of dystroglycanopathy. Neuropathol Appl Neurobiol. 2017 Jun;43(4):330-345
1	J:269775 Dillon GM, Tyler WA, Omuro KC, Kambouris J, Tyminski C, Henry S, Haydar TF, Beffert U, Ho A, CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Neuron. 2017 Mar 22;93(6):1344-1358.e5
1*	J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283
1*	J:186654 Gao Z, Poon HY, Li L, Li X, Palmesino E, Glubrecht DD, Colwill K, Dutta I, Kania A, Pawson T, Godbout R, Splice-mediated motif switching regulates disabled-1 phosphorylation and SH2 domain interactions. Mol Cell Biol. 2012 Jul;32(14):2794-808
1	J:298804 Han JS, Hino K, Li W, Reyes RV, Canales CP, Miltner AM, Haddadi Y, Sun J, Chen CY, La Torre A, Simo S, CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):23073-23084
1*	J:74239 Herrick TM, Cooper JA, A hypomorphic allele of dab1 reveals regional differences in reelin-Dab1 signaling during brain development. Development. 2002 Feb 1;129(3):787-96
1	J:91679 Herrick TM, Cooper JA, High affinity binding of Dab1 to Reelin receptors promotes normal positioning of upper layer cortical plate neurons. Brain Res Mol Brain Res. 2004 Jul 26;126(2):121-8
1*	J:38446 Howell BW, Gertler FB, Cooper JA, Mouse disabled (mDab1): a Src binding protein implicated in neuronal development. EMBO J. 1997 Jan 2;16(1):121-32
1	J:43647 Howell BW, Hawkes R, Soriano P, Cooper JA, Neuronal position in the developing brain is regulated by mouse disabled-1 [see comments]. Nature. 1997 Oct 16;389(6652):733-7
1*	J:54100 Howell BW, Herrick TM, Cooper JA, Reelin-induced tyrosine phosphorylation of disabled 1 during neuronal positioning. Genes Dev. 1999 Mar 15;13(6):643-8
1	J:331698 Ishii K, Kohno T, Sakai K, Hattori M, Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation. Mol Cell Neurosci. 2022 Nov 23;124:103794
1	J:106956 Isosaka T, Hattori K, Yagi T, NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice. Brain Res. 2006 Feb 16;1073-1074:11-9
1	J:77532 Keshvara L, Magdaleno S, Benhayon D, Curran T, Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling. J Neurosci. 2002 Jun 15;22(12):4869-77
1	J:299731 Kohno T, Ishii K, Hirota Y, Honda T, Makino M, Kawasaki T, Nakajima K, Hattori M, Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. J Neurosci. 2020 Oct 21;40(43):8248-8261
1	J:191935 Lee GH, Kim SH, Homayouni R, D'Arcangelo G, Dab2ip regulates neuronal migration and neurite outgrowth in the developing neocortex. PLoS One. 2012;7(10):e46592
1	J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78
1	J:240398 Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017 Mar 22;37(12):3181-3191
1	J:293055 Okugawa E, Ogino H, Shigenobu T, Yamakage Y, Tsuiji H, Oishi H, Kohno T, Hattori M, Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice. Sci Rep. 2020 Mar 11;10(1):4471
1	J:217514 Onoue A, Takeuchi M, Kohno T, Hattori M, Aberrant fragment of Dab1 protein is present in yotari mouse. Neurosci Res. 2014 Nov;88:23-7
1	J:240000 Park JY, Hughes LJ, Moon UY, Park R, Kim SB, Tran K, Lee JS, Cho SH, Kim S, The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state. Development. 2016 Jan 01;143(1):133-46
1*	J:138266 Sato Y, Taoka M, Sugiyama N, Kubo K, Fuchigami T, Asada A, Saito T, Nakajima K, Isobe T, Hisanaga S, Regulation of the interaction of Disabled-1 with CIN85 by phosphorylation with Cyclin-dependent kinase 5. Genes Cells. 2007 Dec;12(12):1315-27
1	J:43504 Sheldon M, Rice DS, D'Arcangelo G, Yoneshima H, Nakajima K, Mikoshiba K , Howell BW , Cooper JA , Goldowitz D , Curran T, Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice [see comments]. Nature. 1997 Oct 16;389(6652):730-3
1	J:205551 Simo S, Cooper JA, Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors. Dev Cell. 2013 Nov 25;27(4):399-411
1*	J:55691 Trommsdorff M, Gotthardt M, Hiesberger T, Shelton J, Stockinger W , Nimpf J , Hammer RE , Richardson JA , Herz J, Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell. 1999 Jun 11;97(6):689-701
1	J:129038 Wang X, Nadarajah B, Robinson AC, McColl BW, Jin JW, Dajas-Bailador F, Boot-Handford RP, Tournier C, Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death. Mol Cell Biol. 2007 Nov;27(22):7935-46
1	J:242933 Whittaker DE, Riegman KL, Kasah S, Mohan C, Yu T, Sala BP, Hebaishi H, Caruso A, Marques AC, Michetti C, Smachetti ME, Shah A, Sabbioni M, Kulhanci O, Tee WW, Reinberg D, Scattoni ML, Volk H, McGonnell I, Wardle FC, Fernandes C, Basson MA, The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest. 2017 Mar 01;127(3):874-887
1	J:291718 Yamakage Y, Kato M, Hongo A, Ogino H, Ishii K, Ishizuka T, Kamei T, Tsuiji H, Miyamoto T, Oishi H, Kohno T, Hattori M, A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum. Mol Cell Neurosci. 2019 Oct;100:103401